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What are diabetes problems?
Too much sugar in the blood for a long time causes diabetes problems. This high blood sugar can damage many parts of the body, such as the kidneys, heart, and blood vessels. Diabetes problems can be scary, but there is a lot you can do to prevent them or slow them down. This booklet is about kidney problems caused by diabetes. You will learn the things you can do each day and during each year to stay healthy and prevent diabetes problems. High blood sugar can cause kidney problems. What should I do each day to stay healthy with diabetes?
What do my kidneys do?
The kidneys act as filters to clean the blood. They get rid of waste and extra fluid. The tiny filters throughout the kidneys are called glomeruli (glo-MEHR-yoo-lie). When kidneys are healthy, the artery (AR-ter-ee) brings blood and waste from the bloodstream into the kidney. The glomeruli clean the blood. Then waste and extra fluid go out into the urine through the ureter. Clean blood goes out of the kidney and back into the bloodstream through the vein. You have two kidneys. Your kidneys clean your blood and make urine. Here is a simplified drawing of one. How can I prevent diabetes kidney problems?
Is there a medicine to slow down kidney damage?
Yes. Your doctor might ask you to take a medicine called an ACE inhibitor (in-HIB-it-ur). This medicine helps control blood pressure. ACE inhibitors also help people with diabetes to slow down kidney damage by keeping the kidneys from cleaning out too much protein. New medicines now being tested may also hold promise. Your doctor might ask you to take an ACE inhibitor to control your blood pressure. How can my doctor protect my kidneys during special x-ray tests?If you have kidney damage, the liquid, called a contrast agent, used for special x-ray tests can make your kidney damage worse. Your doctor can give you extra water before and after the x-ray to protect your kidneys. Or your doctor may decide to order a test that does not use a contrast agent. How can diabetes hurt my kidneys?
When kidneys are working well, the glomeruli keep protein inside your body. You need the protein to stay healthy. High blood sugar and high blood pressure damage the kidneys’ glomeruli. When the kidneys are damaged, the protein leaks out of the kidneys into the urine. Damaged kidneys do not do a good job of cleaning out waste and extra fluids. So not enough waste and fluids go out of the body as urine. Instead, they build up in your blood. An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin (al-BYOO-min) into the urine. With more damage, the kidneys leak more and more protein. This problem is called proteinuria (PRO-tee-NOOR-ee-uh). More and more wastes build up in the blood. This damage gets worse until the kidneys fail. Diabetic nephropathy (neh-FROP-uh-thee) is the medical word for kidney problems caused by diabetes. No protein is leaking from the healthy kidney. Protein is leaking from the unhealthy kidney. What can I do if I have diabetes kidney problems?
Once you have kidney damage, you cannot undo it. But you can slow it down or stop it from getting worse by doing the things listed in the Keeping blood pressure under control helps to keep your kidneys healthy. How will I know if my kidneys fail?
At first, you cannot tell. Kidney failure from diabetes happens so slowly that you may not feel sick at all for many years. You will not feel sick even when your kidneys do only half the job of normal kidneys. You may not feel any signs of kidney failure until your kidneys have almost stopped. However, getting your urine and blood tested every year can tell you if your kidneys are still working. Once your kidneys fail, you may feel sick to your stomach and feel tired all the time. Your skin may turn yellow. You may feel puffy, and your hands and feet may swell from extra fluid in your body. You may feel sick to your stomach when your kidneys stop working. What happens if my kidneys fail?
First, you will need dialysis (dy-AL-ih-sis) treatment. Dialysis is a treatment that does the work your kidneys used to do. There are two types of dialysis. You and your doctor will decide what type will work best for you. Dialysis is a treatment that takes waste products and extra fluid out of your body.
Second, you may be able to have a kidney transplant. This operation gives you a new kidney. The kidney can be from a close family member, friend, or someone you do not know. You may be on dialysis for a long time. Many people are waiting for new kidneys. A new kidney must be a good match for your body. Will I know if I start to have kidney problems?No. You will know you have kidney problems only if your doctor tests your urine for protein. Do not wait for signs of kidney damage to have your urine tested. How can I find out if I have kidney problems?Each year make sure your doctor tests a sample of your urine to see if your kidneys are leaking albumin. If your kidneys are not leaking a lot of albumin, ask your doctor to check your urine for even smaller amounts of albumin. This is called microalbumin (MY-kro-al-BYOO-min). It is good news if your kidneys are not leaking even small amounts of albumin. Then you and your doctor know your kidneys are working well. Will my doctor do other kidney tests?Maybe. Your doctor might test your blood to measure the amounts of creatinine (kree-AT-ih-nin) and urea (yoo-REE-uh). These are waste products your body makes. If your kidneys are not cleaning them out of your blood, they can build up and make you sick. Your doctor might also ask you to collect your urine in a large container for a whole day or just overnight. For more information
Diabetes Teachers (nurses, dietitians, pharmacists, and other health professionals) To find a diabetes teacher near you, call the American Association of Diabetes Educators toll-free at 1-800-TEAMUP4 (1-800-832-6874), or look on the Internet at http://www.aadenet.org/ and click on "Find an Educator." Recognized Diabetes Education Programs (teaching programs approved by the American Diabetes Association) To find a program near you, call toll-free at 1-800-DIABETES (1-800-342-2383), or see www.diabetes.org/education/edustate2.asp on the Internet. Dietitians To find a dietitian near you, call the American Dietetic Association's National Center for Nutrition and Dietetics toll-free at 1-800-366-1655, or look on the Internet at http://www.eatright.org/ and click on "Find a Dietitian." Government The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health. To learn more about kidney problems, write or call NKUDIC, 3 Information Way, Bethesda, MD 20892-3580, (301) 654-4415; or see http://www.niddk.nih.gov/ on the Internet. More in the seriesThe "Prevent Diabetes Problems" series includes seven booklets that can help you learn more about how to prevent diabetes problems.
For free single printed copies of these booklets, call, write, fax, or email the
AcknowledgmentsThe National Diabetes Information Clearinghouse thanks the people who helped review or field-test this booklet.
For American Association of Diabetes Educators
For American Diabetes Association
Diabetes Research and Training Center
Diabetes Research and Training Center
Diabetes Research and Training Center
Grady Health System
Health Care Financing
Indian Health Service
Indian Health Service
Medlantic Research Center
Texas Diabetes Council
National Diabetes Information Clearinghouse
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). NIDDK is part of the National Institutes of Health under the U.S. Department of Health and Human Services. Established in 1978, the clearinghouse provides information about diabetes to people with diabetes and to their families, health care professionals, and the public. NDIC answers inquiries; develops, reviews, and distributes publications; and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes. Publications produced by the clearinghouse are carefully reviewed for scientific accuracy, content, and readability. This e-text is not copyrighted. The clearinghouse encourages users of this e-pub to duplicate and distribute as many copies as desired. NIH Publication No. 00-4281
Copyright © 1998-2002 SLM & Healthy Living
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